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A tumor cord model for Doxorubicin delivery and dose optimization in solid tumors
BACKGROUND: Doxorubicin is a common anticancer agent used in the treatment of a number of neoplasms, with the lifetime dose limited due to the potential for cardiotoxocity. This has motivated efforts to develop optimal dosage regimes that maximize anti-tumor activity while minimizing cardiac toxicit...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736154/ https://www.ncbi.nlm.nih.gov/pubmed/19664243 http://dx.doi.org/10.1186/1742-4682-6-16 |