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Glutamic Acid Decarboxylase-Derived Epitopes with Specific Domains Expand CD4(+)CD25(+) Regulatory T Cells

BACKGROUND: CD4(+)CD25(+) regulatory T cell (Treg)-based immunotherapy is considered a promising regimen for controlling the progression of autoimmune diabetes. In this study, we tested the hypothesis that the therapeutic effects of Tregs in response to the antigenic epitope stimulation depend on th...

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Detalles Bibliográficos
Autores principales: Chen, Guojiang, Han, Gencheng, Feng, Jiannan, Wang, Jianan, Wang, Renxi, Xu, Ruonan, Shen, Beifen, Qian, Jiahua, Li, Yan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736381/
https://www.ncbi.nlm.nih.gov/pubmed/19759824
http://dx.doi.org/10.1371/journal.pone.0007034