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Glutamic Acid Decarboxylase-Derived Epitopes with Specific Domains Expand CD4(+)CD25(+) Regulatory T Cells
BACKGROUND: CD4(+)CD25(+) regulatory T cell (Treg)-based immunotherapy is considered a promising regimen for controlling the progression of autoimmune diabetes. In this study, we tested the hypothesis that the therapeutic effects of Tregs in response to the antigenic epitope stimulation depend on th...
Autores principales: | Chen, Guojiang, Han, Gencheng, Feng, Jiannan, Wang, Jianan, Wang, Renxi, Xu, Ruonan, Shen, Beifen, Qian, Jiahua, Li, Yan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736381/ https://www.ncbi.nlm.nih.gov/pubmed/19759824 http://dx.doi.org/10.1371/journal.pone.0007034 |
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