The Schizosaccharomyces pombe Hsp104 Disaggregase Is Unable to Propagate the [PSI (+)] Prion

The molecular chaperone Hsp104 is a crucial factor in the acquisition of thermotolerance in yeast. Under stress conditions, the disaggregase activity of Hsp104 facilitates the reactivation of misfolded proteins. Hsp104 is also involved in the propagation of fungal prions. For instance, the well-char...

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Detalles Bibliográficos
Autores principales: Sénéchal, Patrick, Arseneault, Geneviève, Leroux, Alexandre, Lindquist, Susan, Rokeach, Luis A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736384/
https://www.ncbi.nlm.nih.gov/pubmed/19759825
http://dx.doi.org/10.1371/journal.pone.0006939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736384/
https://www.ncbi.nlm.nih.gov/pubmed/19759825
http://dx.doi.org/10.1371/journal.pone.0006939

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