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High Efficiency Lipid-Based siRNA Transfection of Adipocytes in Suspension

BACKGROUND: Fully differentiated adipocytes are considered to be refractory to introduction of siRNA via lipid-based transfection. However, large scale siRNA-based loss-of-function screening of adipocytes using either electroporation or virally-mediated transfection approaches can be prohibitively c...

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Detalles Bibliográficos
Autores principales: Kilroy, Gail, Burk, David H., Floyd, Z. Elizabeth
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736387/
https://www.ncbi.nlm.nih.gov/pubmed/19759827
http://dx.doi.org/10.1371/journal.pone.0006940