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A Novel Liposome-Based Adjuvant CAF01 for Induction of CD8(+) Cytotoxic T-Lymphocytes (CTL) to HIV-1 Minimal CTL Peptides in HLA-A*0201 Transgenic Mice

BACKGROUND: Specific cellular cytotoxic immune responses (CTL) are important in combating viral diseases and a highly desirable feature in the development of targeted HIV vaccines. Adjuvants are key components in vaccines and may assist the HIV immunogens in inducing the desired CTL responses. In se...

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Detalles Bibliográficos
Autores principales: Gram, Gregers Jacob, Karlsson, Ingrid, Agger, Else Marie, Andersen, Peter, Fomsgaard, Anders
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736401/
https://www.ncbi.nlm.nih.gov/pubmed/19759892
http://dx.doi.org/10.1371/journal.pone.0006950