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Effects of 4-methylimidazole on cerebral glutamate decarboxylase activity and specific GABA receptor binding in mice

4-Methylimidazole (4MeI) is a tremorogenic and convulsive agent of concern both in human and veterinary toxicology. The in vitro effects of 4MeI (5 μM–20 mM) on cerebral glutamate decarboxylase (GAD) activity and (in concentrations up to 50 mM) on binding of [(3)H]GABA to cerebral GABA receptors wer...

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Detalles Bibliográficos
Autores principales: Sivertsen, Tore, Nygaard, Ann-Kristin, Mathisen, Gro, Fonnum, Frode
Formato: Texto
Lenguaje:English
Publicado: Informa Healthcare 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736537/
https://www.ncbi.nlm.nih.gov/pubmed/19730755
http://dx.doi.org/10.1080/15376510802488173