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Conserved Expression Patterns Predict microRNA Targets

microRNAs (miRNAs) are major regulators of gene expression and thereby modulate many biological processes. Computational methods have been instrumental in understanding how miRNAs bind to mRNAs to induce their repression but have proven inaccurate. Here we describe a novel method that combines expre...

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Detalles Bibliográficos
Autores principales: Ritchie, William, Rajasekhar, Megha, Flamant, Stephane, Rasko, John E. J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736581/
https://www.ncbi.nlm.nih.gov/pubmed/19779543
http://dx.doi.org/10.1371/journal.pcbi.1000513