The 3′ Region of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to Its Core and Is Required for Full Insulator Activity

Chromatin insulators separate active transcriptional domains and block the spread of heterochromatin in the genome. Studies on the chicken hypersensitive site-4 (cHS4) element, a prototypic insulator, have identified CTCF and USF-1/2 motifs in the proximal 250 bp of cHS4, termed the “core”, which pr...

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Detalles Bibliográficos
Autores principales: Arumugam, Paritha I., Urbinati, Fabrizia, Velu, Chinavenmeni S., Higashimoto, Tomoyasu, Grimes, H. Leighton, Malik, Punam
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736623/
https://www.ncbi.nlm.nih.gov/pubmed/19746166
http://dx.doi.org/10.1371/journal.pone.0006995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736623/
https://www.ncbi.nlm.nih.gov/pubmed/19746166
http://dx.doi.org/10.1371/journal.pone.0006995

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