A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system

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Covalent attachment of ubiquitin to substrates is crucial to protein degradation, transcription regulation and cell signalling. Highly specific interactions between ubiquitin-conjugating enzymes (E2) and ubiquitin protein E3 ligases fulfil essential roles in this process. We performed a global yeast...

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Detalles Bibliográficos
Autores principales: van Wijk, Sjoerd J L, de Vries, Sjoerd J, Kemmeren, Patrick, Huang, Anding, Boelens, Rolf, Bonvin, Alexandre M J J, Timmers, H Th Marc
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736652/
https://www.ncbi.nlm.nih.gov/pubmed/19690564
http://dx.doi.org/10.1038/msb.2009.55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736652/
https://www.ncbi.nlm.nih.gov/pubmed/19690564
http://dx.doi.org/10.1038/msb.2009.55

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