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A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system
Covalent attachment of ubiquitin to substrates is crucial to protein degradation, transcription regulation and cell signalling. Highly specific interactions between ubiquitin-conjugating enzymes (E2) and ubiquitin protein E3 ligases fulfil essential roles in this process. We performed a global yeast...
Autores principales: | van Wijk, Sjoerd J L, de Vries, Sjoerd J, Kemmeren, Patrick, Huang, Anding, Boelens, Rolf, Bonvin, Alexandre M J J, Timmers, H Th Marc |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736652/ https://www.ncbi.nlm.nih.gov/pubmed/19690564 http://dx.doi.org/10.1038/msb.2009.55 |
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