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Genome-scale gene/reaction essentiality and synthetic lethality analysis
Synthetic lethals are to pairs of non-essential genes whose simultaneous deletion prohibits growth. One can extend the concept of synthetic lethality by considering gene groups of increasing size where only the simultaneous elimination of all genes is lethal, whereas individual gene deletions are no...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736653/ https://www.ncbi.nlm.nih.gov/pubmed/19690570 http://dx.doi.org/10.1038/msb.2009.56 |