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Large-scale identification of genetic design strategies using local search

In the past decade, computational methods have been shown to be well suited to unraveling the complex web of metabolic reactions in biological systems. Methods based on flux–balance analysis (FBA) and bi-level optimization have been used to great effect in aiding metabolic engineering. These methods...

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Detalles Bibliográficos
Autores principales: Lun, Desmond S, Rockwell, Graham, Guido, Nicholas J, Baym, Michael, Kelner, Jonathan A, Berger, Bonnie, Galagan, James E, Church, George M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736654/
https://www.ncbi.nlm.nih.gov/pubmed/19690565
http://dx.doi.org/10.1038/msb.2009.57