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MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression

BACKGROUND: MicroRNAs are small non-coding RNA molecules, which regulate central mechanisms of tumorigenesis. In colorectal tumours, the combination of gain of 8q and 13q is one of the major factors associated with colorectal adenoma to adenocarcinoma progression. Functional studies on the miR-17-92...

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Detalles Bibliográficos
Autores principales: Diosdado, B, van de Wiel, M A, Terhaar Sive Droste, J S, Mongera, S, Postma, C, Meijerink, W J H J, Carvalho, B, Meijer, G A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736819/
https://www.ncbi.nlm.nih.gov/pubmed/19672269
http://dx.doi.org/10.1038/sj.bjc.6605037