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Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2α overexpression

BACKGROUND: Activator protein-2α (AP-2α) is a transcription factor that belongs to the family of AP-2 proteins that have essential roles in tumorigenesis. Indeed, AP-2α is considered as a tumour-suppressor gene in different tissues such as colonic, prostatic or breast epithelial cells. Moreover, AP-...

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Detalles Bibliográficos
Autores principales: Jonckheere, N, Fauquette, V, Stechly, L, Saint-Laurent, N, Aubert, S, Susini, C, Huet, G, Porchet, N, Van Seuningen, I, Pigny, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736821/
https://www.ncbi.nlm.nih.gov/pubmed/19672266
http://dx.doi.org/10.1038/sj.bjc.6605190