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Regulation of Neph3 gene in podocytes – key roles of transcription factors NF-κB and Sp1

BACKGROUND: Neph3 (filtrin) is expressed in the glomerular podocytes where it localizes at the specialized cell adhesion structures of the foot processes called slit diaphragms which form the outermost layer of the glomerular filtration barrier. Neph3 protein shows homology and structural similarity...

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Detalles Bibliográficos
Autores principales: Ristola, Mervi, Arpiainen, Satu, Saleem, Moin A, Mathieson, Peter W, Welsh, Gavin I, Lehtonen, Sanna, Holthöfer, Harry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736951/
https://www.ncbi.nlm.nih.gov/pubmed/19703278
http://dx.doi.org/10.1186/1471-2199-10-83