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Distinct retroelement classes define evolutionary breakpoints demarcating sites of evolutionary novelty

BACKGROUND: Large-scale genome rearrangements brought about by chromosome breaks underlie numerous inherited diseases, initiate or promote many cancers and are also associated with karyotype diversification during species evolution. Recent research has shown that these breakpoints are nonrandomly di...

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Detalles Bibliográficos
Autores principales: Longo, Mark S, Carone, Dawn M, Green, Eric D, O'Neill, Michael J, O'Neill, Rachel J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736999/
https://www.ncbi.nlm.nih.gov/pubmed/19630942
http://dx.doi.org/10.1186/1471-2164-10-334