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Decreased PM(10) Exposure Attenuates Age-Related Lung Function Decline: Genetic Variants in p53, p21, and CCND1 Modify This Effect

BACKGROUND: Decreasing exposure to airborne particulates was previously associated with reduced age-related decline in lung function. However, whether the benefit from improved air quality depends on genetic background is not known. Recent evidence points to the involvement of the genes p53 and p21...

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Detalles Bibliográficos
Autores principales: Imboden, Medea, Schwartz, Joel, Schindler, Christian, Curjuric, Ivan, Berger, Wolfgang, Liu, Sally L.J., Russi, Erich W., Ackermann-Liebrich, Ursula, Rochat, Thierry, Probst-Hensch, Nicole M.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737020/
https://www.ncbi.nlm.nih.gov/pubmed/19750108
http://dx.doi.org/10.1289/ehp.0800430