Silencing by small RNAs is linked to endosome trafficking

Small RNAs direct RNA induced silencing complexes (RISCs) to regulate the stability and translation of mRNAs1,2. RISCs associated with target mRNAs often accumulate in discrete cytoplasmic foci known as GW-bodies3. However, RISC proteins can associate with membrane compartments such as the Golgi and...

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Detalles Bibliográficos
Autores principales: Lee, Young Sik, Pressman, Sigal, Andress, Arlise P., Kim, Kevin, White, Jamie L., Cassidy, Justin J., Li, Xin, Lubell, Kim, Lim, Do Hwan, Cho, Ik Sang, Nakahara, Kenji, Preall, Jonathan B., Bellare, Priya, Sontheimer, Erik J., Carthew, Richard W.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737091/
https://www.ncbi.nlm.nih.gov/pubmed/19684574
http://dx.doi.org/10.1038/ncb1930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737091/
https://www.ncbi.nlm.nih.gov/pubmed/19684574
http://dx.doi.org/10.1038/ncb1930

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