Islet Endothelial Activation and Oxidative Stress Gene Expression Is Reduced by IL-1Ra Treatment in the Type 2 Diabetic GK Rat

BACKGROUND: Inflammation followed by fibrosis is a component of islet dysfunction in both rodent and human type 2 diabetes. Because islet inflammation may originate from endothelial cells, we assessed the expression of selected genes involved in endothelial cell activation in islets from a spontaneo...

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Detalles Bibliográficos
Autores principales: Lacraz, Grégory, Giroix, Marie-Hélène, Kassis, Nadim, Coulaud, Josiane, Galinier, Anne, Noll, Christophe, Cornut, Mélanie, Schmidlin, Fabien, Paul, Jean-Louis, Janel, Nathalie, Irminger, Jean-Claude, Kergoat, Micheline, Portha, Bernard, Donath, Marc Y., Ehses, Jan A., Homo-Delarche, Françoise
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737103/
https://www.ncbi.nlm.nih.gov/pubmed/19742300
http://dx.doi.org/10.1371/journal.pone.0006963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737103/
https://www.ncbi.nlm.nih.gov/pubmed/19742300
http://dx.doi.org/10.1371/journal.pone.0006963

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