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Lubiprostone Stimulates Duodenal Bicarbonate Secretion in Rats

BACKGROUND: Lubiprostone, a bicyclic fatty acid, is used for the treatment of chronic constipation. No published study has addressed the effect of lubiprostone on intestinal ion secretion in vivo. AIM: The aim of this study was to test the hypothesis that lubiprostone augments duodenal HCO(3)(−) sec...

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Detalles Bibliográficos
Autores principales: Mizumori, Misa, Akiba, Yasutada, Kaunitz, Jonathan D.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737111/
https://www.ncbi.nlm.nih.gov/pubmed/19657734
http://dx.doi.org/10.1007/s10620-009-0907-0