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Cancer cell–derived microparticles bearing P-selectin glycoprotein ligand 1 accelerate thrombus formation in vivo

Recent publications have demonstrated the presence of tissue factor (TF)–bearing microparticles (MPs) in the blood of patients suffering from cancer. However, whether these MPs are involved in thrombosis remains unknown. We show that pancreatic and lung cancer cells produce MPs that express active T...

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Detalles Bibliográficos
Autores principales: Thomas, Grace M., Panicot-Dubois, Laurence, Lacroix, Romaric, Dignat-George, Françoise, Lombardo, Dominique, Dubois, Christophe
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737159/
https://www.ncbi.nlm.nih.gov/pubmed/19667060
http://dx.doi.org/10.1084/jem.20082297