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Cancer cell–derived microparticles bearing P-selectin glycoprotein ligand 1 accelerate thrombus formation in vivo
Recent publications have demonstrated the presence of tissue factor (TF)–bearing microparticles (MPs) in the blood of patients suffering from cancer. However, whether these MPs are involved in thrombosis remains unknown. We show that pancreatic and lung cancer cells produce MPs that express active T...
Autores principales: | Thomas, Grace M., Panicot-Dubois, Laurence, Lacroix, Romaric, Dignat-George, Françoise, Lombardo, Dominique, Dubois, Christophe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737159/ https://www.ncbi.nlm.nih.gov/pubmed/19667060 http://dx.doi.org/10.1084/jem.20082297 |
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