Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

Innate immune cells detect pathogens via pattern recognition receptors (PRRs), which signal for initiation of immune responses to infection. Studies with Dectin-1, a PRR for fungi, have defined a novel innate signaling pathway involving Syk kinase and the adaptor CARD9, which is critical for inducin...

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Detalles Bibliográficos
Autores principales: Robinson, Matthew J., Osorio, Fabiola, Rosas, Marcela, Freitas, Rui P., Schweighoffer, Edina, Groß, Olaf, Verbeek, J. Sjef, Ruland, Jürgen, Tybulewicz, Victor, Brown, Gordon D., Moita, Luis Ferreira, Taylor, Philip R., Reis e Sousa, Caetano
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737172/
https://www.ncbi.nlm.nih.gov/pubmed/19703985
http://dx.doi.org/10.1084/jem.20082818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737172/
https://www.ncbi.nlm.nih.gov/pubmed/19703985
http://dx.doi.org/10.1084/jem.20082818

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