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The RISC component VIG is a target for dsRNA-independent protein kinase activity in Drosophila S2 cells

RNA interference (RNAi) is mediated by a multicomponent RNA-induced silencing complex (RISC). Here we examine the phosphorylation state of three Drosophila RISC-associated proteins, VIG, R2D2 and a truncated form of Argonaute2 devoid of the nonconserved N-terminal glutamine-rich domain. We show that...

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Detalles Bibliográficos
Autores principales: Ivanov, Konstantin I, Tselykh, Timofey V, Heino, Tapio I, Mäkinen, Kristiina
Formato: Texto
Lenguaje:English
Publicado: Library Publishing Media 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737197/
https://www.ncbi.nlm.nih.gov/pubmed/19771199