A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs

RNA interference (RNAi) is an evolutionary conserved gene silencing mechanism in which small interfering RNA (siRNA) mediates the sequence specific degradation of mRNA. The recent discovery that exogenously delivered siRNA can trigger RNAi in mammalian cells raises the possibility to use this techno...

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Detalles Bibliográficos
Autores principales: ter Brake, Olivier, Berkhout, Ben
Formato: Texto
Lenguaje:English
Publicado: Library Publishing Media 2005
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737200/
https://www.ncbi.nlm.nih.gov/pubmed/19771206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737200/
https://www.ncbi.nlm.nih.gov/pubmed/19771206

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