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Frog Prince transposon-based RNAi vectors mediate efficient gene knockdown in human cells

We have developed a stable RNA interference (RNAi) delivery system that is based on the Frog Prince transposable element. This plasmid-based vector system combines the gene silencing capabilities of H1 polymerase III promoter-driven short hairpin RNAs (shRNA) with the advantages of stable and effici...

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Detalles Bibliográficos
Autores principales: Kaufman, Christopher D, Izsvák, Zsuzsanna, Katzer, Andrea, Ivics, Zoltán
Formato: Texto
Lenguaje:English
Publicado: Library Publishing Media 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737204/
https://www.ncbi.nlm.nih.gov/pubmed/19771210