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Systematic analysis of the role of target site accessibility in the activity of DNA enzymes

We employed an approach using oligonucleotide scanning arrays and computational analysis to conduct a systematic analysis of the interaction between catalytic nucleic acids (DNA enzymes or DNAzymes) and long RNA targets. A radio-labelled transcript representing mRNA of Xenopus cyclin B5 was hybridis...

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Detalles Bibliográficos
Autores principales: Doran, Graeme, Sohail, Muhammad
Formato: Texto
Lenguaje:English
Publicado: Library Publishing Media 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737222/
https://www.ncbi.nlm.nih.gov/pubmed/19771227