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Distinct subdomains of the KCNQ1 S6 segment determine channel modulation by different KCNE subunits
Modulation of voltage-gated potassium (K(V)) channels by the KCNE family of single transmembrane proteins has physiological and pathophysiological importance. All five KCNE proteins (KCNE1–KCNE5) have been demonstrated to modulate heterologously expressed KCNQ1 (K(V)7.1) with diverse effects, making...
Autores principales: | Vanoye, Carlos G., Welch, Richard C., Daniels, Melissa A., Manderfield, Lauren J., Tapper, Andrew R., Sanders, Charles R., George, Alfred L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737226/ https://www.ncbi.nlm.nih.gov/pubmed/19687231 http://dx.doi.org/10.1085/jgp.200910234 |
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