Different pathways for activation and deactivation in Ca(V)1.2: a minimal gating model

Point mutations in pore-lining S6 segments of Ca(V)1.2 shift the voltage dependence of activation into the hyperpolarizing direction and significantly decelerate current activation and deactivation. Here, we analyze theses changes in channel gating in terms of a circular four-state model accounting...

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Detalles Bibliográficos
Autores principales: Beyl, Stanislav, Kügler, Philipp, Kudrnac, Michaela, Hohaus, Annette, Hering, Steffen, Timin, Eugen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737230/
https://www.ncbi.nlm.nih.gov/pubmed/19687230
http://dx.doi.org/10.1085/jgp.200910272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737230/
https://www.ncbi.nlm.nih.gov/pubmed/19687230
http://dx.doi.org/10.1085/jgp.200910272

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