Cargando…
Different pathways for activation and deactivation in Ca(V)1.2: a minimal gating model
Point mutations in pore-lining S6 segments of Ca(V)1.2 shift the voltage dependence of activation into the hyperpolarizing direction and significantly decelerate current activation and deactivation. Here, we analyze theses changes in channel gating in terms of a circular four-state model accounting...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737230/ https://www.ncbi.nlm.nih.gov/pubmed/19687230 http://dx.doi.org/10.1085/jgp.200910272 |