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Differential regulation of gene expression in mouse spermatogonial cells after blocking c-kit-SCF interaction with RNAi

c-Kit, the gene product of the W locus is a receptor tyrosine kinase that regulates the survival, growth and differentiation of spermatogonial cells (SGCs). Stem cell factor (SCF), the gene product of the steel (Sl) locus is the ligand for c-kit. Normal function of SGCs requires cross-talk between c...

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Detalles Bibliográficos
Autores principales: Sikarwar, Arun P, Rambabu, Murali K, Reddy, K V R
Formato: Texto
Lenguaje:English
Publicado: Library Publishing Media 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737241/
https://www.ncbi.nlm.nih.gov/pubmed/19771240