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Distinct High-Profile Methylated Genes in Colorectal Cancer

BACKGROUND: Mutations and promoters' methylation of a set of candidate cancer genes (CAN genes) are associated with progression of colorectal cancer (CRC). We hypothesized that these genes' promoters are inactivated through epigenetic silencing and may show a different profile in high-risk...

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Detalles Bibliográficos
Autores principales: Mokarram, Pooneh, Kumar, Krishan, Brim, Hassan, Naghibalhossaini, Fakhraddin, Saberi-firoozi, Mehdi, Nouraie, Mehdi, Green, Robert, Lee, Ed, Smoot, Duane T., Ashktorab, Hassan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737306/
https://www.ncbi.nlm.nih.gov/pubmed/19750230
http://dx.doi.org/10.1371/journal.pone.0007012