G-Quadruplex DNA Bound by a Synthetic Ligand is Highly Dynamic

[Image: see text] Using single molecule fluorescence resonance energy transfer, we investigated the interaction between a quadruplex-binding ligand and the human telomeric G-quadruplex. The binding of quinolinecarboxamide macrocycle to telomeric DNA was essentially irreversible and selectively induc...

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Detalles Bibliográficos
Autores principales: Jena, Prakrit V., Shirude, Pravin S., Okumus, Burak, Laxmi-Reddy, Katta, Godde, Frédéric, Huc, Ivan, Balasubramanian, Shankar, Ha, Taekjip
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737377/
https://www.ncbi.nlm.nih.gov/pubmed/19685880
http://dx.doi.org/10.1021/ja903408r

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737377/
https://www.ncbi.nlm.nih.gov/pubmed/19685880
http://dx.doi.org/10.1021/ja903408r

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