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BDNF Val66Met Polymorphism Influences Age Differences in Microstructure of the Corpus Callosum

Brain-derived neurotrophic factor (BDNF) plays an important role in neuroplasticity and promotes axonal growth, but its secretion, regulated by a BDNF gene, declines with age. The low-activity (met) allele of common polymorphism BDNF val66met is associated with reduced production of BDNF. We examine...

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Detalles Bibliográficos
Autores principales: Kennedy, Kristen M., Rodrigue, Karen M., Land, Susan J., Raz, Naftali
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737488/
https://www.ncbi.nlm.nih.gov/pubmed/19738930
http://dx.doi.org/10.3389/neuro.09.019.2009