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Possible role of amyloid-beta, adenine nucleotide translocase and cyclophilin-D interaction in mitochondrial dysfunction of Alzheimer's disease

Alzheimer's disease (AD) is a common neurodegenerative disease characterized by both extra- as well as intracellular deposition of amyloid beta peptides (Aβ). The accumulation of Aβ in mitochondria is associated with mitochondrial dysfunction and oxidative stress in AD. Recent evidences suggest...

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Detalles Bibliográficos
Autores principales: Singh, Prabhakar, Suman, Shubhankar, Chandna, Sudhir, Das, Taposh Kumar
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737500/
https://www.ncbi.nlm.nih.gov/pubmed/19759867