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The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation

BACKGROUND: The high intracellular salt concentration required to maintain a halophilic lifestyle poses challenges to haloarchaeal proteins that must stay soluble, stable and functional in this extreme environment. Proliferating cell nuclear antigen (PCNA) is a fundamental protein involved in mainta...

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Detalles Bibliográficos
Autores principales: Winter, Jody A, Christofi, Panayiotis, Morroll, Shaun, Bunting, Karen A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737543/
https://www.ncbi.nlm.nih.gov/pubmed/19698123
http://dx.doi.org/10.1186/1472-6807-9-55