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Perturbation of Mouse Retinal Vascular Morphogenesis by Anthrax Lethal Toxin

Lethal factor, the enzymatic moiety of anthrax lethal toxin (LeTx) is a protease that inactivates mitogen activated protein kinase kinases (MEK or MKK). In vitro and in vivo studies demonstrate LeTx targets endothelial cells. However, the effects of LeTx on endothelial cells are incompletely charact...

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Detalles Bibliográficos
Autores principales: Bromberg-White, Jennifer L., Boguslawski, Elissa, Duesbery, Nicholas S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737623/
https://www.ncbi.nlm.nih.gov/pubmed/19750016
http://dx.doi.org/10.1371/journal.pone.0006956