Inhibitors of MyD88-Dependent Proinflammatory Cytokine Production Identified Utilizing a Novel RNA Interference Screening Approach

BACKGROUND: The events required to initiate host defenses against invading pathogens involve complex signaling cascades comprised of numerous adaptor molecules, kinases, and transcriptional elements, ultimately leading to the production of proinflammatory cytokines, such as tumor necrosis factor alp...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, John S., Kim, Yun C., Morrison, Sherie L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737626/
https://www.ncbi.nlm.nih.gov/pubmed/19753301
http://dx.doi.org/10.1371/journal.pone.0007029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737626/
https://www.ncbi.nlm.nih.gov/pubmed/19753301
http://dx.doi.org/10.1371/journal.pone.0007029

Ejemplares similares