A Novel Scoring Approach for Protein Co-Purification Data Reveals High Interaction Specificity

Large-scale protein interaction networks (PINs) have typically been discerned using affinity purification followed by mass spectrometry (AP/MS) and yeast two-hybrid (Y2H) techniques. It is generally recognized that Y2H screens detect direct binary interactions while the AP/MS method captures co-comp...

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Detalles Bibliográficos
Autores principales: Yu, Xueping, Ivanic, Joseph, Wallqvist, Anders, Reifman, Jaques
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738424/
https://www.ncbi.nlm.nih.gov/pubmed/19779545
http://dx.doi.org/10.1371/journal.pcbi.1000515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738424/
https://www.ncbi.nlm.nih.gov/pubmed/19779545
http://dx.doi.org/10.1371/journal.pcbi.1000515

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