Cargando…
A Novel Scoring Approach for Protein Co-Purification Data Reveals High Interaction Specificity
Large-scale protein interaction networks (PINs) have typically been discerned using affinity purification followed by mass spectrometry (AP/MS) and yeast two-hybrid (Y2H) techniques. It is generally recognized that Y2H screens detect direct binary interactions while the AP/MS method captures co-comp...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738424/ https://www.ncbi.nlm.nih.gov/pubmed/19779545 http://dx.doi.org/10.1371/journal.pcbi.1000515 |