Complementation of diverse HIV-1 Env defects through cooperative subunit interactions: a general property of the functional trimer

BACKGROUND: The HIV-1 Env glycoprotein mediates virus entry by catalyzing direct fusion between the virion membrane and the target cell plasma membrane. Env is composed of two subunits: gp120, which binds to CD4 and the coreceptor, and gp41, which is triggered upon coreceptor binding to promote the...

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Detalles Bibliográficos
Autores principales: Salzwedel, Karl, Berger, Edward A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738651/
https://www.ncbi.nlm.nih.gov/pubmed/19671162
http://dx.doi.org/10.1186/1742-4690-6-75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738651/
https://www.ncbi.nlm.nih.gov/pubmed/19671162
http://dx.doi.org/10.1186/1742-4690-6-75

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