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Complementation of diverse HIV-1 Env defects through cooperative subunit interactions: a general property of the functional trimer
BACKGROUND: The HIV-1 Env glycoprotein mediates virus entry by catalyzing direct fusion between the virion membrane and the target cell plasma membrane. Env is composed of two subunits: gp120, which binds to CD4 and the coreceptor, and gp41, which is triggered upon coreceptor binding to promote the...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738651/ https://www.ncbi.nlm.nih.gov/pubmed/19671162 http://dx.doi.org/10.1186/1742-4690-6-75 |