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Genistein Inhibition of Topoisomerase IIα Expression Participated by Sp1 and Sp3 in HeLa Cell

Genistein (4′, 5, 7-trihydroxyisoflavone) is an isoflavone compound obtained from plants that has potential applications in cancer therapy. However, the molecular mechanism of the action of genistein on cancer cell apoptosis is not well known. In this study, we investigated the effect of genistein o...

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Detalles Bibliográficos
Autores principales: Zhou, Najing, Yan, Yunli, Li, Wenling, Wang, Yanling, Zheng, Lifen, Han, Shuo, Yan, Yongxin, Li, Yunzhi
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738924/
https://www.ncbi.nlm.nih.gov/pubmed/19742137
http://dx.doi.org/10.3390/ijms10073255