Zebrafish IGF Genes: Gene Duplication, Conservation and Divergence, and Novel Roles in Midline and Notochord Development

Insulin-like growth factors (IGFs) are key regulators of development, growth, and longevity. In most vertebrate species including humans, there is one IGF-1 gene and one IGF-2 gene. Here we report the identification and functional characterization of 4 distinct IGF genes (termed as igf-1a, -1b, -2a,...

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Detalles Bibliográficos
Autores principales: Zou, Shuming, Kamei, Hiroyasu, Modi, Zubin, Duan, Cunming
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738950/
https://www.ncbi.nlm.nih.gov/pubmed/19759899
http://dx.doi.org/10.1371/journal.pone.0007026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738950/
https://www.ncbi.nlm.nih.gov/pubmed/19759899
http://dx.doi.org/10.1371/journal.pone.0007026

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