Anti-Leukemia Activity of MS-275 Histone Deacetylase Inhibitor Implicates 4-1BBL/4-1BB Immunomodulatory Functions

Histone deacetylase inhibitors (HDACi) have demonstrated promising therapeutic potential in clinical trials for hematological malignancies. HDACi, such as SAHA/Vorinostat, Trichostatin A, and MS-275 were found to induce apoptosis of leukemic blasts through activation of the death receptor pathway an...

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Detalles Bibliográficos
Autores principales: Vire, Bérengère, de Walque, Stéphane, Restouin, Audrey, Olive, Daniel, Van Lint, Carine, Collette, Yves
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738963/
https://www.ncbi.nlm.nih.gov/pubmed/19759901
http://dx.doi.org/10.1371/journal.pone.0007085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738963/
https://www.ncbi.nlm.nih.gov/pubmed/19759901
http://dx.doi.org/10.1371/journal.pone.0007085

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