Jak3 Is Involved in Dendritic Cell Maturation and CCR7-Dependent Migration

BACKGROUND: CCR7-mediated signalling is important for dendritic cell maturation and homing to the lymph nodes. We have previously demonstrated that Jak3 participates in the signalling pathway of CCR7 in T lymphocytes. METHODOLOGY AND PRINCIPAL FINDINGS: Here, we used Jak3(−/−) mice to analyze the ro...

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Detalles Bibliográficos
Autores principales: Rivas-Caicedo, Ana, Soldevila, Gloria, Fortoul, Teresa I., Castell-Rodríguez, Andrés, Flores-Romo, Leopoldo, García-Zepeda, Eduardo A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738966/
https://www.ncbi.nlm.nih.gov/pubmed/19759904
http://dx.doi.org/10.1371/journal.pone.0007066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738966/
https://www.ncbi.nlm.nih.gov/pubmed/19759904
http://dx.doi.org/10.1371/journal.pone.0007066

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