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Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein
BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) Tat protein is a major viral transactivator required for HIV-1 replication. In the nucleus Tat greatly stimulates the synthesis of full-length transcripts from the HIV-1 promoter by causing efficient transcriptional elongation. Tat induces...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739156/ https://www.ncbi.nlm.nih.gov/pubmed/19671151 http://dx.doi.org/10.1186/1742-4690-6-74 |