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Does negative auto-regulation increase gene duplicability?
BACKGROUND: A prerequisite for a duplication to spread through and persist in a given population is retaining expression of both gene copies. Yet changing a gene's dosage is frequently detrimental to fitness. Consequently, dosage-sensitive genes are less likely to duplicate. However, in cases w...
Autores principales: | Warnecke, Tobias, Wang, Guang-Zhong, Lercher, Martin J, Hurst, Laurence D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739200/ https://www.ncbi.nlm.nih.gov/pubmed/19664220 http://dx.doi.org/10.1186/1471-2148-9-193 |
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