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A Computational Analysis of ATP Binding of SV40 Large Tumor Antigen Helicase Motor

Simian Virus 40 Large Tumor Antigen (LTag) is an efficient helicase motor that unwinds and translocates DNA. The DNA unwinding and translocation of LTag is powered by ATP binding and hydrolysis at the nucleotide pocket between two adjacent subunits of an LTag hexamer. Based on the set of high-resolu...

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Detalles Bibliográficos
Autores principales: Shi, Yemin, Liu, Hanbin, Gai, Dahai, Ma, Jianpeng, Chen, Xiaojiang S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739275/
https://www.ncbi.nlm.nih.gov/pubmed/19779548
http://dx.doi.org/10.1371/journal.pcbi.1000514