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A Computational Analysis of ATP Binding of SV40 Large Tumor Antigen Helicase Motor
Simian Virus 40 Large Tumor Antigen (LTag) is an efficient helicase motor that unwinds and translocates DNA. The DNA unwinding and translocation of LTag is powered by ATP binding and hydrolysis at the nucleotide pocket between two adjacent subunits of an LTag hexamer. Based on the set of high-resolu...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739275/ https://www.ncbi.nlm.nih.gov/pubmed/19779548 http://dx.doi.org/10.1371/journal.pcbi.1000514 |